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Vaccines

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Both you and the medical system benefit from it. Vaccination allows you to avoid severe progression of the disease and death. Vaccinated people also have a lower risk of contracting mild coronavirus (the immunity achieved by the vaccine is 70-95%, depending on the vaccine and individual indicators).

If you are vaccinated and happen to get infected, you already have the COVID-19 antibodies and are protected better against the virus. The virus level in your organism is lower, your body sheds fewer virus particles, and the chances of infecting people close to you are lower than they would be for a sick person who has not been vaccinated.

Last updated: 08.04.2021 16:06

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With these vaccines, the genetic material of the pathogen is delivered into the organism in the form of either DNA or RNA, and based on the information contained in it, the organism itself will synthesize the part of the pathogen necessary for the creation of immunity, i.e. the antigen. As a rule, this is some protein of the pathogen, in the case of the coronavirus the spike protein on its surface. One way of describing the situation would be that if an organism needs food daily, in the case of one vaccine a ready meal is delivered, in the case of another the organism is delivered a recipe and the organism itself is capable of preparing the food with the help of the recipe.

Compared to a protein, the mRNA is a simpler molecule and thus the production of mRNA is generally faster than the production of vaccines that have been in use up until now. The idea of vaccines based on mRNA is actually already decades old and this type of vaccines have been tested in clinical studies for different infectious diseases. For different reasons, none of them have been taken into use on humans thus far. There is reason to hope that technological development will allow it now.

More information is available here: https://somblogi.wordpress.com/2020/12/22/triin-suvi-ja-pille-saalik-ravimiametist-selgitavad-kuidas-toimivad-meie-kehas-koroonavaktsiini-erinvad-tuubid/

Last updated: 27.12.2020 17:16

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Additional information on the blogpost of the Ministry of Social Affairs: https://somblogi.wordpress.com/2020/12/22/triin-suvi-ja-pille-saalik-ravimiametist-selgitavad-kuidas-toimivad-meie-kehas-koroonavaktsiini-erinvad-tuubid/

  • Inactivated vaccines contain a killed virus particle.
  • Component vaccine contains a virus antigen produced in a laboratory. It does not contain the virus itself.
  • Virus-like particle -- different parts of the virus are synthesized in a laboratory and put together into a single virus-like particle. It lacks the genetic material of the virus and it does not reproduce itself.
  • mRNA vaccine contains mRNA in a fat bubble, based on which the cells of our body produce the virus antigen.
  • A vaccine based on a virus vector where a virus vector delivers DNA into a cell in which a virus antigen is produced based on the DNA.

Last updated: 27.12.2020 17:17

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As several different vaccines are being developed and coming to the market, their characteristics are certain to somewhat differ from each other.

Whether a vaccine is suitable or unsuitable for somebody is noted on the information sheet of the vaccine.

Who should be vaccinated and how is best known to the medical worker who carries out the vaccination.

Last updated: 27.12.2020 17:08

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The objective of the vaccines is to imitate the virus. We have to fool the organism with the vaccine, give it the impression that it is being attacked by SARS-CoV-2. With the help of the vaccine, the immune system learns to recognize the spike proteins of the virus and fight against the virus more effectively.

No medicine or vaccine is 100% safe. What we can say with full certainty, however, is that the danger of getting severe side effects from the vaccine is hundreds, if not thousands, of times smaller than contracting the coronavirus and suffering through it severely.

The side effects of the vaccines are temporary and no long-term side effects have been established up until now. COVID-19, however, causes long-term damage often. Thus using new vaccines is a calculated risk that clearly favours the vaccines.

Read more from here: https://www.ut.ee/et/teadus/teadlaste-vastused-koroonakusimustele (in Estonian)

Last updated: 08.04.2021 14:54

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Viruses mutating is a regular process. All mutations do not lead to reduced efficacy of the developed vaccines but the genetic changes in virus strains are still followed closely in order to evaluate their effect on the vaccines that have been or are being developed.

Last updated: 27.12.2020 17:08

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Even though a certain immune protection occurs even after the first dose, it is not strong enough, which is why it is important to get both shots if the vaccine requires a two-dose course.

Last updated: 16.03.2021 16:24

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In a situation where most of the countries in the world are in the process of procuring COVID-19 vaccines and the demand surpasses the supply, Estonia would not have the market power to be successful in negotiating with the manufacturers alone.

The European Union has 27 member states with almost 450 million residents behind it. It is possible for countries to have independent negotiations with the vaccine manufacturers but even the larger EU member states have decided in favour of joint EU negotiations and joint EU pre-purchase agreements.

Thus, the European Commission has been authorized to procure COVID-19 vaccines for all member states and it was in the interests of Estonia to accede to this joint procurement in order to guarantee the availability of COVID-19 vaccine for the residents of Estonia.

Last updated: 27.12.2020 17:14

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The vaccines that are being processed and reviewed by the European Medicines Agency for receiving a marketing authorisation do not contain mercury particles or other unknown compounds. Finding microchips or other such things in vaccines belongs to the sphere of conspiracy theories. All medicines that receive a marketing authorisation in the European Union are checked, safe, of high quality and effective. All ingredients of the vaccine are listed on the information sheet of the vaccine.

Last updated: 27.12.2020 17:14

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Component vaccines, inactivated vaccines, and vaccines based on virus-like particles. Additionally, vaccines based on mRNA and virus vector.

Last updated: 27.12.2020 17:14

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As of December 23, 2020, the European Commission has concluded pre-purchase agreements with six vaccine manufacturers: AstraZeneca, Sanofi, Jannsen Pharmaceutica NV, Pfizer/BioNTech, Curevac, and Moderna.

Estonia has joined five of those pre-purchase agreements and a decision about joining the Sanofi pre-purchase agreement will be made at the beginning of 2021.

The EU member states, including Estonia, have not yet received the pre-purchase agreement with the vaccine manufacturer Novavax.

At the request of several member states, negotiations have also begun with the vaccine manufacturer Valneva.

Last updated: 27.12.2020 17:14

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One of the most important goals of the COVID-19 vaccines is to avoid severe (requiring hospitalisation) and mortal forms of the disease. All vaccines in use fulfil this goal very effectively, all vaccines offer a practically hundred percent protection from severe forms of the disease.

Vaccination also manages to avoid most of the mild and moderate cases of the COVID-19 disease: the Pfizer vaccine does it at the rate of 95% and the Moderna vaccine at the rate of 94%.

The effectiveness of the AstraZeneca vaccine in avoiding symptomatic disease is 60% (even though it is possible to increase the effectiveness to over 80% by using different dosing schemes).

Last updated: 09.03.2021 13:17

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More information about the coronavirus and restrictions related to it is available calling 1247 (from abroad +372 600 1247).